Above: A six-stranded triple-crossover (TX) DNA Junction (again). See Ned Seeman's ACS interview for more background (also again).
Sixteen years (!) since its release, it's still something I return to regularly because it does a very specific set of operations very well (I'd say that even if I didn't help with the development). Having made the leap on one of my machines to get used to anything new in 24.04 ("Noble Numbat." And re-testing all my other usual apt-gets to see what else I'm using from a decade ago that still has a chance of loading), trying NanoEngineer-1 (NE1) was on my short list of "if this doesn't work, I ain't upgrading" apps.
Bryan Bishop's github repo for Version 1.1.1 is alive (some highlights from the old gallery included) and the program is still kicking with this new install. I note that googling "NanoEngineer-1" now takes you to his page first above others, which is great.
This post is just an FYI – NE1 still runs like a charm. From his download link and how-to, it's a simple few steps.
My only installs on 24.04 include:
sudo apt-get install mesa-utils libx11-dev
And I'm not entirely sure about needing the libx11-dev. The snippet below taken from the github readme will have you running:
# download the ready-made chroot archive (600 MB)
wget http://diyhpl.us/~bryan/irc/nanoengineer/nanoengineer-chroot.tar.gz
# extract the chroot
tar -zxvf nanoengineer-chroot.tar.gz
# mount these things if you want the GUI to work
for i in etc/resolv.conf tmp proc dev; do sudo mount --bind /$i nanoengineer-chroot/$i; done
# allow connections from other uids over the local X11 socket
xhost +local:
# jump in
sudo chroot nanoengineer-chroot/
# now run nanoengineer
su nanoengineeruser -c "python ~/code/nanoengineer/cad/src/main.py"
And with that, NE1. No effort to optimize, I've not tried loading a REALLY BIG mmp file to see what might crash, but I'm happy to have at least three or four more years of access to my old mmp ("molecular machine part") files before, at worst, jumping to VirtualBox.