For interested parties, this article also marks the first official mention (to the best of my knowledge) of our upcoming MOST/TACNY/CNYO hosting of International Observe The Moon Night on Saturday, October 8th. Additional details to follow, but expect the observing to happen somewhere around The MOST itself.
Extra-special thanks to Nick Lamendola from the Astronomy Section of the Rochester Academy of Science (image above, taken from the grounds of my new observing stomping grounds at the Farash Center – click for a larger view) for the use of his Perseid composite as the article opener (one of the benefits of being a member of several local clubs is the listserve content – and the many fantastic images that fly by on a weekly basis).
Posting for historical purposes, given the great recording and video that came from the session.
The Methodist Bells (bandcampfacebook) had the pleasure of performing a 3/4 set on Sunday, August 21st at (my first drum teacher, Ron Keck’s) Subcat Studios for Sub Rosa Session #32. Closing for the Bells (well, I think it’s funny) was recently-US-returned-and-immediately-thereafter-Binghamton-bound Colin Phils (bandcampfacebook), who put on a fantastic trio show (and, with one of the wooden USBs in tow, I can say that their previous two albums are excellent as well).
“The band. The band. THE BAND!” Adam, me, Leah, Clem, Jeremy, et Maurice.
Alice In The Sky, featuring an Allis On The Ground
In the interest of aggregation, quick post linking the first two in a new series of astronomy articles on newyorkupstate.com and syracuse.com. There’s an old adage in academia – “You don’t really know something until you can teach it.” To that end, these articles and their associated research prep are great fun and yet another excellent excuse to go out at night and compare the planetarium apps to the real thing (for which both Starry Night Pro and Stellarium are excellent organizational proxies. I’m currently leaning on Stellarium for the imagery because others who might get bit by the astronomy bug can download it for free and follow along. That said, Starry Night Pro is still my workhorse for fine detail as Stellarium continues to develop).
When the article series was first proposed, the goal for the Syracuse Media Group folks was to provide people in upstate some basic information for what was up and about in the night sky – when you step outside, what’s there to find? My hope is to provide the non-observer and novice observer just enough information to whet the appetite, hopefully coaxing readers to take some quality looks and, if all goes well, to seek out their local astronomy club for some serious observing – and learning.
Night sky-gazing in Upstate NY: What to look for in July
The series started just in time to highlight the Perseid Meteor Shower (and get its first linking to thanks to Glenn Coin’sarticle as we approached the Perseid peak), then August was chock full of interesting planetary events. The August article was also a first exposure to the issues of episodic astronomy – how to be as minimally referential as possible in any single article to previous articles (which is not easy given how much the search for constellations historically has involved the finding of a bright one to orient observers to a dimmer one).
July hit 78 shares on newyorkupstate.com, August hit 4400 – at that rate, the whole world will see the October article.
Dr. Stuart Forster (a.k.a. STU – full caps) was one of the THE fixtures in the CNY amateur astronomy scene and his name still comes up regularly, often as part of some pearl of wisdom being imparted to new observers and seasoned members alike (I’ll leave you to read the top of the Stuventory page for more info about STU and to check out links to some of his images on the Syracuse Astronomical Society website). The trials and tribulations of Ryan Goodson and myself to handle the massive equipment collection we’ve come to refer to as the “Stuventory” is olde hat to local observers who’ve kept track of the process from a far. The sorting, documenting, and distribution of the Stuventory has taught us both about how very unique the hobby of amateur astronomy can be when you step beyond the 1×7 mm binoculars in your head and effort the collection of more and more photons.
The snapshot below shows the state of swv as of 3 December 2014. On the bright side (minus a friendly conspiracy to get someone else in trouble), I can say with some certainty that Serwan performed the content-ectomy (twitter: @S3RW4N, current email (although I suspect it won’t last long): serwan_007 – at cymbal – hotmail.com, on the Facebook, etc. All sites subject to change as people try to track him/her down post-attack (he/she’s been prolific if nothing else)).
The back cover picture shows two views at 150 degree rotation of vitamin B12 conjugated to the potent anti- hyperglycemia peptide glucagon-like peptide-1 (GLP-1). The conjugate displays similar receptor binding and agonism to unconjugated GLP-1, including insulin potentiation from human transplant pancreatic islet cells, which bodes well for oral delivery of GLP-1 through the B12 dietary pathway. For more details, see the Communication by Robert P. Doyle et al. on p. 582 ff.
I’ve been fortunate twice this year to have the Central New York (CNY) Skeptics force me to commit to a presentation topics I thought were worth presenting. As a complement to the audio that will appear at some point on the CNY Skeptics site, I’ve posted the non-animated slides as a PDF below. And the press photo’s from a way-back Excelsior Cornet Band gig where I had too long a wait between playing and marching.
The MedChemComm post also provides the caption for the cover (below), which I reproduce below for context:
Oral delivery of drugs aims to open up new areas of peptide/protein therapeutics associated with the removal for a need for injections. The major problems facing oral delivery of peptides/proteins is hydrolysis/proteolysis in the gastrointestinal tract and an inefficient uptake mechanism for peptides/proteins from the tract. Robert P. Doyle et al. are interested in the use of the vitamin B12 dietary uptake pathway to address these hurdles. In this paper Doyle et al. report the synthesis, purification and characterisation of a new B12-insulin conjugate attached between the B12 ribose hydroxyl group and insulin PheB1.